Description
4F-4-MAR (4-Fluoro-4-methylaminorex) Abstract
Despite the fact that 4F-4-MAR (4-Fluoro-4-methylaminorex) of the new psychoactive substances.seized in 2015 were synthetic cathinones. the number of these derivatives decreasing .
As a consequence of the unfavourable effects reported by users. cathinone analogues is expect to short. And it is likel.
the same moiety change. apply for the preparation of synthetic cathinones .
apply in the near future to other stimulants. the search for favourable alternatives substances. This is evidence by the increase in new report substances belong to stimulant classes other than cathinones. One of the possible candidates for a new backbone from which to base new stimulants is aminorex, which is classified as a Schedule I substance by the Drug Enforcement Administration.
Abstract
Despite 4F-4-MAR (4-Fluoro-4-methylaminorex) the fact of new cathinones. the number of these derivatives decreasing in last years.
probably as a consequence of the unfavourable effects.it is like that the same moiety change apply for the synthetic cathinones.
apply in the near future to other stimulants.for favourable alternatives to controllsubstances. One of the possible candidates for a new backbone from which to base new stimulants is aminorex, which is classified as a Schedule I substance by the Drug Enforcement Administration.
Identifying the 4′F-4-MAR
When the compound was injected into the UHPLC-HRMS, a single chromatographic peak at 2.63 min was observed in the total ion chromatogram. Figure 3 shows the low energy and high energy spectra obtained by HRMS for this chromatographic peak. The low energy spectrum corresponding to this peak showed an ion at m/z 195.0933, which would correspond to the protonated molecule of the compound .
COMPOSITION
According to the aminorex elemental this putative derivative should contain an extra methyl group .a fluorine atom on the aminorex structure. The high energy spectrum of the chromatographic peak showed six important fragment. This specific loss report in literature for two aminorex derivatives, the para-methyl-4-methylaminorex (4,4′-DMAR) and the 3′,4′-methylenedioxy-4-methylaminorex (MDMAR). The loss of CHNO from [M + H]+ produces the formation of an N-epoxide structure on the molecule, in the same way than 4,4′-DMAR and MDMAR.
EFFECTS
Additionally, as can be seen in the archived hive thread referenced describing pleasant effects at fairly low doses and no immediate negative side effects. This is very useful for producers. because it removes some of the uncertainty regard the recreational potential of this substance.
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