threo-4-Methylmethylphenidate (4-MeTMP) is a stimulant drug related to methylphenidate. It is slightly less potent than methylphenidate and has relatively low efficacy at blocking dopamine reuptake despite its high binding affinity, which led to its investigation as a possible substitute drug for treatment of stimulant abuse (cf. nocaine). On the other hand, several other simple ring-substituted derivatives of threo-methylphenidate such as the 4-fluoro and 3-chloro compounds are more potent than methylphenidate both in efficacy as dopamine reuptake inhibitors and in animal drug discrimination assays.

threo-4-Methylmethylphenidate

(4-MeTMP) is a stimulant drug related to methylphenidate. It is slightly less potent than methylphenidate and has relatively low efficacy at blocking dopamine reuptake despite its high binding affinity, which led to its investigation as a possible substitute drug for treatment of stimulant abuse (cf. nocaine). On the other hand, several other simple ring-substituted derivatives of threo-methylphenidate such as the 4-fluoro and 3-chloro compounds are more potent than methylphenidate both in efficacy as dopamine reuptake inhibitors and in animal drug discrimination assays. 

threo-4-Methylmethylphenidate (4-MeTMP)

is a stimulant drug related to methylphenidate. It is slightly less potent than methylphenidate and has relatively low efficacy at blocking dopamine reuptake despite its high binding affinity, which led to its investigation as a possible substitute drug for treatment of stimulant abuse (cf. nocaine). On the other hand, several other simple ring-substituted derivatives of threo-methylphenidate such as the 4-fluoro and 3-chloro compounds are more potent than methylphenidate both in efficacy as dopamine reuptake inhibitors and in animal drug discrimination assays

EFFECTS

Additionally, as can be seen in the archived hive thread referenced  describing pleasant effects at fairly low doses and no immediate negative side effects. This is very useful for producers. because it removes some of the uncertainty regard the recreational potential of this substance.

COMPOSITION

According to the aminorex elemental  this putative derivative should contain an extra methyl group .a fluorine atom on the aminorex structure. The high energy spectrum of the chromatographic peak showed six important fragment. This specific loss report in literature for two aminorex derivatives, the para-methyl-4-methylaminorex (4,4′-DMAR) and the 3′,4′-methylenedioxy-4-methylaminorex (MDMAR). The loss of CHNO from [M + H]⁺ produces the formation of an N-epoxide structure on the molecule, in the same way than 4,4′-DMAR and MDMAR.